Red Snappers
نویسنده
چکیده
limitations. In a longitudinal study of visceral leishmaniasis in Bangladesh, Bern et al. reported loss of LST sensitivity attributed to antigen-production issues, such as standardization and documentation of sensitivity, potency, and stability of leishmanin antigens (5). Also, prior treatment with immunosuppressive agents, which influence cell-mediated immunity, may decrease LST prognostic potency similarly to changes observed for the tuberculin skin test in similar settings (6). Variations in specificities and sensitivities limit the diagnostic potential of available diagnostic tools. The context of immunosuppression further contributes to the diagnostic complications and increases the need for additional research in leishmaniasis diagnostics.
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